CENTRAL ATROPHY
نویسندگان
چکیده
منابع مشابه
Large annular plaque with central atrophy on nose.
Indian J Dermatol Venereol Leprol | September-October 2009 | Vol 75 | Issue 5 of all routine investigations were within normal limits. Results of HIV antibody test and Mantoux test were negative. Collagen profile was within normal limits. Histological examination of the tissue from the lesion on the left side of nose showed multiple follicular and parakeratotic invaginations in the epidermis, a...
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A 61-yr-old male presented with apparent idiopathic central sleep apnoea but after 4 yrs developed features of autonomic, cerebellar and extrapyramidal dysfunction consistent with a diagnosis of multiple system atrophy (MSA). Though central sleep apnoea can occur in multiple sleep apnoea, it is less frequent than obstructive sleep apnoea and occurs in the later stages of the disease. The pathog...
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Spinal muscular atrophy (SMA) is a genetic disorder which affect nervous system and is characterized with progressive distal motor neuron weakness. The survival motor neuron (SMN) protein level reduces in patients with SMA. Two different genes code survival motor neuron protein in human genome. Skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory fa...
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Spinal muscular atrophy (SMA) is characterized by motoneuron loss and muscle weakness. However, the structural and functional deficits that lead to the impairment of the neuromuscular system remain poorly defined. By electron microscopy, we previously found that neuromuscular junctions (NMJs) and muscle fibres of the diaphragm are among the earliest affected structures in the severe mouse SMA m...
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Skeletal muscle catabolism is a co-morbidity of many chronic diseases and is the result of systemic inflammation. Although direct inflammatory cytokine action on muscle promotes atrophy, nonmuscle sites of action for inflammatory mediators are less well described. We demonstrate that central nervous system (CNS)-delimited interleukin 1β (IL-1β) signaling alone can evoke a catabolic program in m...
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ژورنال
عنوان ژورنال: The Journal of Nervous and Mental Disease
سال: 1917
ISSN: 0022-3018
DOI: 10.1097/00005053-191710000-00003